Endocrine Abstracts

BACKGROUND: Lymphocytic hypophysitis (LHy) is an uncommon inflammatory disorder of the pituitary with features mimicking those of sellar tumours, thereby often being misdiagnosed. However, no long-term follow-up studies have been published.OBJECT: To evaluate the clinical/radiological characteristics and the prognosis of patients with LHy.PATIENTS-METHODS: The records of the patients who presented to the Department of Endocrinology...

Introduction: Gestational diabetes mellitus (GDM) has been associated with adverse maternal and fetal/neonatal outcomes. The aim of this case-control study was to compare women whose pregnancy was complicated with GDM, diagnosed by the new International Association of Diabetes and Pregnancy Study Groups (IADPSG) criteria, with a control group of healthy pregnant women as far as large-for-gestational-age (LGA) neonates and macrosomia are concerned.Methods...

BACKGROUND: Acromegaly is a chronic debilitating disease, which can also affect calcium metabolism. Hypercalciuria is a common finding but hypercalcaemia is rare and has been reported in 0-10% of cases in various studies involving small number of patients.AIM: To investigate the prevalence and aetiology of hypercalcaemia among patients with acromegaly.PATIENTS AND METHODS: The medical records of 145 patients who presented to our De...

INTRODUCTION: Although IGF-I is considered to reflect the daily GH secretion, its value in establishing the diagnosis of adult growth hormone deficiency (GHD) and in predicting the presence of further anterior pituitary deficits has not been elucidated in a large series.AIM: To evaluate the diagnostic utility of a subnormal IGF-I in patients with GHD and to investigate whether a low IGF-I is associated with the presence of further anterior pituitary defi...